Translocation of the tetracycline resistance determinant from R100-1 to the Escherichia coli K-12 chromosome.
نویسندگان
چکیده
Pairs of normally incompatible derivatives of R100-1 (one ChlS TetR, the other ChilR TetS) were forced to coexist in a recA host by selection for ChlR TetR cells. After many generations stable derivatives were isolated. The analysis of none independent stabilization experiments showed that in each case TetR was translocated from the plasmid to the chromosome of the host. No evidence for the joint integration of other plasmid genes (those controlling transfer, antibiotic resistance, incompatibility, or origin of transfer replication) was obtained. One of the chromosomal TetR determinants was mapped close to metE.
منابع مشابه
Monitoring the prevalence of the tetracycline efflux genes among E. coli isolated from chicken colibacillosis
BACKGROUND: Avian Colibacillosis can lead to important economic losses in the poultry industry. Escherichia coli the causative agent of this disease has acquired resistance to different antibiotics, including tetracycline. OBJECTIVES: This study was carried out to detect the distribution of tetracycline Group І efflux genes genes among E.coli isolates from from avian colibacillosis in Iran by P...
متن کاملEvaluation of the antibiotic resistance and prevalence of uropathogenic Escherichia coli and detection of traT gene in isolated from patients referred to Abadan hospitals during 2017-2018
Objective: Escherichia coli is one of the most important causes agents of urinary tract infection in human. Thus, identification of Escherichia coli resistance patterns seems to be necessary. traT gene has been reported variable in Escherichia coli strains isolated from urinary tract infection. Therefore, the aim of this study was to investigate the prevalence of uropathogenic Escherichia coli ...
متن کاملStudy of Sensibility and Antimicrobial Resistance in Escherichia coli Isolated from Urinary Tract Infection in Tabriz City
Background & Objective: Urinary infection is one of the most prevalent infectious diseases, and Escherichia coli is the most important cause of urinary infections. This study was done with the aim of surveying the amount of susceptibility and resistance among the strains of Escherichia coli isolated from those who referred to the private laboratories in the Iranian city of Tabriz.Materials...
متن کاملEvaluation of resistance genes in Escherichia coli isolated from toilets in the Islamic Azad University, Mashhad and genome sequencing (tet B, tet A, tet R, OXA 10 and OXA 48) in tetracycline-resistant strains
Aims and Background: E. coli is a normal flora of the human and animal intestine that sometimes causes pathogenesis in the intestine and urinary tract. The aim of this study is to investigate resistance genes in E. coli isolated from toilets in the Islamic Azad University of Mashhad and perform genome sequencing in tetracycline-resistant strains. Methods: This cross-sectional study was perform...
متن کاملSurvey and identification of Resistance Genes of Sulfanamide (sul2, sul3) and Tetracycline Tet (A), tet (C), tet (D) and intI Integron Genes in Escherichia Coli Isolated from Mastitis Samples
Background and Aims: Escherichia coli is a natural microflora of the human heart and all the warm animals. Mastitis is a disease caused by various pathogens. One of the important factors in the production of mastitis in the livestock is E. coli and is known as peripheral mastitis. The aim of this study was to isolate sulfonamide, integron and tetracycline resistance genes in E.coli isolated fro...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Journal of bacteriology
دوره 124 3 شماره
صفحات -
تاریخ انتشار 1975